SFB1321Projects

Cancer genomics, sequencing, informatics and data integration platform

Principal Investigators: Prof. Klaus A. Kuhn (Institut für Medizinische Informatik, Statistik und Epidemiologie, TUM), Prof. Roland Rad (Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, TUM)

S02 is a platform for cancer genomic analyses that will provide sequencing and bioinformatics support, covering a broad spectrum of applications needed by subprojects. A second aim of S02 is to characterize the genomic landscapes of mouse and human PDAC cell line and organoid resources; and to integrate these genomic analyses with functional and phenotypic data, such as drug screens, histopathology or clinical/prognostic information. These cellular and data resources will be a critical experimental platform for CRC groups to dissect the molecular basis of various phenotypes. All data will be curated and made accessible through an intuitive data analytics and visualization platform.